题 目：Intersection of Bioenergetics and Regenerative Capacity in Male Germline Stem Cells
报告人：Jon Oatley 教授，美国华盛顿州立大学生殖生物学研究中心主任
时 间：2017 年6 月23 日（周五）下午3:30-5:00
地 点：生殖医学国家重点实验室学海楼B214 会议室
主 持：吴 鑫 教授
Jon Oatley，博士。课题组主要研究方向为哺乳动物雄性生殖干细胞的命运决定和调控机制。
Jon Oatley 教授近年代表论文如下：
Zhang T, et al.DMRT1 Is Required for Mouse Spermatogonial Stem Cell Maintenance and Replenishment.
PLoS Genet. 2016 Sep 1;12(9):e1006293.
Hammoud SS, et al. Transcription and imprinting dynamics in developing postnatal male germline stem
cells. Genes Dev. 2015 Nov 1;29(21):2312-24.
Chan, F., et al. (2014). Functional and molecular features of the Id4+ germline stem cell population in
mouse testes. Genes Dev 28(12): 1351-1362.
Yang, Q. E. and J. M. Oatley (2014). Spermatogonial stem cell functions in physiological and pathological
conditions. Curr Top Dev Biol 107: 235-267.
Griswold, M. D. and J. M. Oatley (2013). Concise review: Defining characteristics of mammalian
spermatogenic stem cells. Stem Cells 31(1): 8-11.
Yang, Q. E., et al. (2013). Retinoblastoma protein (RB1) controls fate determination in stem cells and
progenitors of the mouse male germline. Biol Reprod 89(5): 113.
Yang Q., Kaucher A.V., Kim D-W., Oatley M.J., Oatley J.M. 2013. CXCL12/CXCR4 signaling is required
for maintenance of spermatogonial stem cells. J Cell Sci. In Press.
Yang Q., Racicot K.E., Kaucher A.V. Oatley M.J., Oatley J.M. 2013. MicroRNAs 221/222 regulate the
undifferentiated state in mammalian male germ cells. Development. 140: 280-290.
Kaucher A.V., Oatley M.J., Oatley J.M. 2012. Neurog3 is a critical downstream effector of Stat3 regulated
differentiation of mammalian stem and progenitor spermatogonia. Biol. Reprod. 86: 1-11.
Oatley JM, Brinster RL. 2008. Regulation of spermatogonial stem cell self-renewal in mammals. Ann. Rev.
Cell Dev. Biol.; 24: 263-286.