顾亚云，2013-2018年南京医科大学预防医学流行病学硕博连读。2018年至2022年于南京医科大学生殖医学与子代健康全国重点实验室进行博士后研究工作。2022年起以副教授留任。主要研究领域是利用系统流行病学方法整合全基因组测序、小鼠/类器官模型、高通量点突变评价技术如单细胞MPRA技术等系统鉴定生殖相关疾病的遗传和环境病因并解析其分子机制。

代表性论文：(*为共同通讯作者，^#为共同第一作者)

(1)Yayun Gu^#, Yan Zhou^#, Sihan Ju^#, Xiaofei Liu^#, Zicheng Zhang, Jia Guo, Jimiao Gao,Jie Zang, Hao Sun, Qi Chen, Jinghan Wang, Jiani Xu, Yiqun Xu, Yingjia Chen, Yueshuai Guo, Juncheng Dai, Hongxia Ma, Cheng Wang, Guangfu Jin, Chaojun Li, Yankai Xia, Hongbing Shen, Yang Yang, Xuejiang Guo, and Zhibin Hu*. Multi-omics Profiling Visualizes Dynamics of Cardiac Development and Functions. Cell Reports. 2022.

(2)Cheng Wang^#, Yayun Gu^#, Jun Zhou^#, Jie Zang^#, Xiufeng Ling^#, Hong Li^#, Lingmin Hu, Bei Xu, Bo Zhang, Na Qin, Hong Lv, Weiwei Duan, Yue Jiang, Yuanlin He, Tao Jiang, Congcong Chen, Xiumei Han, Kun Zhou, Bo Xu, Xiaoyu Liu, Shiyao Tao, Yangqian Jiang, Jiangbo Du, Juncheng Dai, Feiyang Diao, Chuncheng Lu, Xuejiang Guo, Jiayin Liu, Yuan Lin, Yankai Xia, Guangfu Jin, Hongxia Ma, Hongbing Shen, Zhibin Hu*. Leukocyte telomere length in children born following blastocyst-stage embryo transfer. Nature Medicine. 2022.

(3)Chong D^#, Gu Y^#, Zhang T, Xu Y, Bu D, Chen Z, Xu N, Li L, Zhu X, Wang H, Li Y, Zheng F, Wang D, Li P, Xu L*, Hu Z*, Li C*. Neonatal ketone body elevation regulates postnatal heart development by promoting cardiomyocyte mitochondrial maturation and metabolic reprogramming. Cell Discovery. 2022.

(4)Dongdong Qin, Yayun Gu, Yu Zhang, Shu Wang, Tao Jiang, Yao Wang, Cheng Wang, Chang Chen, Tao Zhang, Weiya Xu, Hanben Wang, Ke Zhang, Liangjun Hu, Lufan Li, Wei Xie, Xin Wu, Zhibin Hu. Phase-separated CCER1 coordinates the histone-to-protamine transition and male fertility. Nat Commun. 2023.

(5) Ru Fang^#, Xiaotong Wang^#, Qiuyuan Xia^#, Ming Zhao, Hao Zhang, Xuan Wang, Shengbing Ye, Kai Cheng, Yan Liang, Yang Cheng*, Yayun Gu*, Qiu Rao*. Nuclear translocation of ASPL-TFE3 fusion protein creates favorable metabolism by mediating autophagy in translocation renal cell carcinoma. Oncogene, 2021.

(6)Yayun Gu#, Cheng Wang#, Rongxuan Zhu, Jianshui Yang, Wenwen Yuan, Yanhui Zhu, Yan Zhou, Na Qin, Hongbing Shen , Hongxia Ma, Hongxia Wang, Xiaoan Liu*, Zhibin Hu*.The cancer-testis gene, MEIOB, sensitizes triple-negative breast cancer to PARP1 inhibitors by inducing homologous recombination deficiency. Cancer Biol Med. 2021.